Articles with "nrps pks" as a keyword



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The Lactococcus lactis KF147 nonribosomal peptide synthetase/polyketide synthase system confers resistance to oxidative stress during growth on plant leaf tissue lysate

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Published in 2018 at "MicrobiologyOpen"

DOI: 10.1002/mbo3.531

Abstract: Strains of Lactococcus lactis isolated from plant tissues possess adaptations that support their survival and growth in plant‐associated microbial habitats. We previously demonstrated that genes coding for a hybrid nonribosomal peptide synthetase/polyketide synthase (NRPS/PKS) system… read more here.

Keywords: lactis; nrps pks; system; plant ... See more keywords
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The Genome of the Plant-Associated Lactic Acid Bacterium Lactococcus lactis KF147 Harbors a Hybrid NRPS-PKS System Conserved in Strains of the Dental Cariogenic Streptococcus mutans

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Published in 2019 at "Current Microbiology"

DOI: 10.1007/s00284-019-01799-1

Abstract: Lactococcus lactis subsp. lactis KF147 as a non-dairy strain from lactic acid bacteria (LAB) can inhabit plant tissues. It can grow on complex carbohydrates derived from plant cell walls. Its genome size is one of… read more here.

Keywords: lactis; nrps pks; system; plant ... See more keywords
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Fungal NRPS-PKS Hybrid Enzymes Biosynthesize New γ-Lactam Compounds, Taslactams A-D, Analogous to Actinomycete Proteasome Inhibitors.

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Published in 2023 at "ACS chemical biology"

DOI: 10.1021/acschembio.2c00830

Abstract: Proteasome inhibitors with γ-lactam structure, such as lactacystin and salinosporamide A, have been isolated from actinomycetes and have attracted attention as lead compounds for anticancer drugs. Previously, we identified a unique enzyme TAS1, which is… read more here.

Keywords: compounds taslactams; proteasome inhibitors; pks hybrid; fungal nrps ... See more keywords