Complete genome sequence of high-yield strain S. lincolnensis B48 and identification of crucial mutations contributing to lincomycin overproduction
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DOI: 10.1016/j.synbio.2020.03.001
Abstract: The lincosamide family antibiotic lincomycin is a widely used antibacterial pharmaceutical generated by Streptomyces lincolnensis, and the high-yield strain B48 produces 2.5 g/L lincomycin, approximately 30-fold as the wild-type strain NRRL 2936. Here, the genome… read more here.
Keywords: overproduction; nrrl 2936; b48; yield strain ... See more keywords