Co-delivery of NS1 and BMP2 mRNAs to murine pluripotent stem cells leads to enhanced BMP-2 expression and osteogenic differentiation.
Sign Up to like & getrecommendations! Published in 2020 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2020.03.045
Abstract: Application of messenger RNA (mRNA) for bone regeneration is a promising alternative to DNA, recombinant proteins and peptides. However, exogenous in vitro transcribed mRNA (IVT mRNA) triggers innate immune response resulting in mRNA degradation and… read more here.
Keywords: expression; murine pluripotent; delivery ns1; ns1 ... See more keywords
N130, N175 and N207 are N-linked glycosylation sites of duck Tembusu virus NS1 that are important for viral multiplication, viremia and virulence in ducklings.
Sign Up to like & getrecommendations! Published in 2021 at "Veterinary microbiology"
DOI: 10.1016/j.vetmic.2021.109215
Abstract: Duck Tembusu virus (DTMUV) is an emerging mosquito-borne flavivirus that has caused acute egg-drop syndrome in egg-laying ducks. DTMUV nonstructural protein 1 (NS1) contains three potential predicted N-linked glycosylation sites at residues 130, 175 and… read more here.
Keywords: n130 n175; n175 n207; linked glycosylation; ns1 ... See more keywords
Secretory glycoprotein NS1 plays a crucial role in the particle formation of flaviviruses
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1010593
Abstract: Flaviviruses, which are globally distributed and cause a spectrum of potentially severe illnesses, pose a major threat to public health. Although Flaviviridae viruses, including flaviviruses, possess similar genome structures, only the flaviviruses encode the non-structural… read more here.
Keywords: formation flaviviruses; ns1 plays; ns1; particle formation ... See more keywords
Influenza A virus NS1 protein represses antiviral immune response by hijacking NF-κB to mediate transcription of type III IFN
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.998584
Abstract: Background Non-structural protein 1 (NS1), one of the viral proteins of influenza A viruses (IAVs), plays a crucial role in evading host antiviral immune response. It is known that the IAV NS1 protein regulates the… read more here.
Keywords: promoter; transcription; ns1; ifnl1 ... See more keywords
The Influence of Preforming Protein Coronas on the Performance of Dengue NS1 Immunoassays
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14112439
Abstract: The effect of preformed protein coronas on immunoassays for Dengue nonstructural protein 1 (NS1) immunoassays was investigated. The composition of the protein corona that forms around nanoparticle–antibody conjugates in human serum was characterized, and selected… read more here.
Keywords: influence preforming; protein coronas; ns1; ns1 immunoassays ... See more keywords
Design and Characterization of Mutated Variants of the Oncotoxic Parvoviral Protein NS1
Sign Up to like & getrecommendations! Published in 2023 at "Viruses"
DOI: 10.3390/v15010209
Abstract: Oncotoxic proteins such as the non-structural protein 1 (NS1), a constituent of the rodent parvovirus H1 (H1-PV), offer a novel approach for treatment of tumors that are refractory to other treatments. In the present study,… read more here.
Keywords: ns1 variants; protein ns1; ns1; protein ... See more keywords