Ellagic Acid as a Potential Inhibitor against the Nonstructural Protein NS3 Helicase of Zika Virus: A Molecular Modelling Study
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DOI: 10.1155/2022/2044577
Abstract: Zika virus is a member of the Flaviviridae family and genus Flavivirus, which has a phylogenetic relationship with spondweni virus. It spreads to humans through a mosquito bite. To identify potential inhibitors for the Zika… read more here.
Keywords: ns3 helicase; helicase; ellagic acid; helicase zika ... See more keywords
Dengue Virus NS4b N-Terminus Disordered Region Interacts with NS3 Helicase C-Terminal Subdomain to Enhance Helicase Activity
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DOI: 10.3390/v14081712
Abstract: Dengue virus replicates its single-stranded RNA genome in membrane-bound complexes formed on the endoplasmic reticulum, where viral non-structural proteins (NS) and RNA co-localize. The NS proteins interact with one another and with the host proteins.… read more here.
Keywords: helicase activity; interaction; ns3 helicase; region ... See more keywords