Structure of the yellow fever NS5 protein reveals conserved drug targets shared among flaviviruses.
Sign Up to like & getrecommendations! Published in 2019 at "Antiviral research"
DOI: 10.1016/j.antiviral.2019.104536
Abstract: Yellow fever virus (YFV) is responsible for devastating outbreaks of Yellow fever (YF) in humans and is associated with high mortality rates. Recent large epidemics and epizootics and exponential increases in the numbers of YF… read more here.
Keywords: yfv; yellow fever; fever; ns5 protein ... See more keywords
The rearrangement of motif F in the flavivirus RNA-directed RNA polymerase.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2017.11.009
Abstract: In the flavivirus genus, the non-structural protein NS5 plays a central role in RNA viral replication and constitutes a major target for drug discovery. One of the prime challenges in the study of NS5 protein… read more here.
Keywords: ns5 protein; flavivirus; rna polymerase;