NS5806 reduces carrageenan-evoked inflammation by suppressing extracellular signal-regulated kinase activation in primary sensory neurons and immune cells.
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DOI: 10.1002/ejp.2123
Abstract: BACKGROUND The compound NS5806 attenuates neuropathic pain via inhibiting extracellular signal-regulated kinase (ERK) activation in neuronal somata located at the dorsal root ganglion (DRG) and superficial spinal dorsal horn. NS5806 also reduces the expansion of… read more here.
Keywords: inflammation; ns5806; extracellular signal; carrageenan evoked ... See more keywords