LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "ns5a ns5b" as a keyword



Hepatitis C virus genotype 1 infection: Prevalence of NS5A and NS5B resistance‐associated substitutions in naïve patients from Argentina

Sign Up to like & get
recommendations! Published in 2019 at "Journal of Medical Virology"

DOI: 10.1002/jmv.25536

Abstract: Direct acting antiviral (DAA) therapy against hepatitis C virus (HCV) increases sustained virologic response rates. Nevertheless, drug resistance has occasionally been associated with failure to DAA. However, the information about the prevalence of NS5A and… read more here.

Keywords: prevalence ns5a; ns5a ns5b; treatment; rass ... See more keywords

Exploring NS3/4A, NS5A and NS5B proteins to design conserved subunit multi-epitope vaccine against HCV utilizing immunoinformatics approaches

Sign Up to like & get
recommendations! Published in 2018 at "Scientific Reports"

DOI: 10.1038/s41598-018-34254-5

Abstract: Hepatitis C virus (HCV) vaccines, designed to augment specific T-cell responses, have been designated as an important aspect of effective antiviral treatment. However, despite the current satisfactory progress of these vaccines, extensive past efforts largely… read more here.

Keywords: ns5a ns5b; hcv; vaccine hcv; immunoinformatics approaches ... See more keywords

Pretreatment Hepatitis C Virus NS5A/NS5B Resistance-Associated Substitutions in Genotype 1 Uruguayan Infected Patients

Sign Up to like & get
recommendations! Published in 2018 at "Disease Markers"

DOI: 10.1155/2018/2514901

Abstract: Hepatitis C Virus (HCV) infection treatment has dramatically changed with the advent of direct-acting antiviral agents (DAAs). However, the efficacy of DAAs can be attenuated by the presence of resistance-associated substitutions (RASs) before and after… read more here.

Keywords: ns5a ns5b; treatment; infected patients; resistance ... See more keywords

In silico analysis of the effect of HCV genotype-specific polymorphisms in Core, NS3, NS5A, and NS5B proteins on T-cell epitope processing and presentation

Sign Up to like & get
recommendations! Published in 2025 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2024.1498069

Abstract: Background HCV genotypes are 30–35% polymorphic at the nucleotide level, while subtypes within the same genotype differ by nearly 20%. Although previous studies have shown the immune escape potential of several mutations within the HCV… read more here.

Keywords: ns3 ns5a; genotype subtype; core ns3; genotype ... See more keywords