Deep sequence analysis of NS5A resistance‐associated substitution changes in patients reinfected with the hepatitis C virus after liver transplantation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Viral Hepatitis"
DOI: 10.1111/jvh.13256
Abstract: The hepatitis C virus (HCV) is an enveloped virus with a positive-senseRNA genome of ~ 9.6 kDa in length. In the body, circulating HCV genomes are highly variable due to the rapidity of RNA virus… read more here.
Keywords: sequence analysis; hepatitis virus; analysis ns5a; ns5a resistance ... See more keywords
Cost-Effectiveness of Testing for NS5A Resistance to Optimize Treatment of Elbasvir/Grazoprevir for Chronic Hepatitis C in China
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.717504
Abstract: Objectives: Baseline presence of nonstructural protein 5A (NS5A) resistance-associated variants can attenuate the efficacy of new direct-acting antivirals. A potential method to attain the higher efficacy would be to screen for NS5A polymorphisms prior to… read more here.
Keywords: treatment; hepatitis china; weeks treatment; treatment testing ... See more keywords