Identification of NS5B resistance against SOFOSBUVIR in hepatitis C virus genotype 3a, naive and treated patients
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Microbiology"
DOI: 10.1111/jam.15754
Abstract: Pakistan has the second highest prevalence of HCV with genotype 3a (GT‐3a) being the most frequently circulating genotype. Currently, resistance‐associated substitutions (RASs) are a major challenge in HCV treatment with direct‐acting antivirals (DAAs). Sofosbuvir (SOF)… read more here.
Keywords: ns5b resistance; resistance sofosbuvir; identification ns5b; genotype ... See more keywords
Identification of NS5B Resistance-Associated Mutations in Hepatitis C Virus Circulating in Treatment Naïve Vietnamese Patients
Sign Up to like & getrecommendations! Published in 2022 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s353605
Abstract: Introduction Treatment of HCV infection with peginterferon and ribavirin results in a low sustained virologic response rate, but has a number of undesirable adverse effects. Direct-acting antivirals (DAAs) offer a high efficacy, low risk, and… read more here.
Keywords: associated mutations; vietnamese patients; ns5b resistance; resistance ... See more keywords