Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia
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DOI: 10.1038/s41467-017-02290-w
Abstract: Effective therapy of acute myeloid leukemia (AML) remains an unmet need. DNA methylcytosine dioxygenase Ten-eleven translocation 1 (TET1) is a critical oncoprotein in AML. Through a series of data analysis and drug screening, we identified… read more here.
Keywords: nsc 370284; myeloid leukemia; acute myeloid; tet1 ... See more keywords