Notch3 regulates ferroptosis via ROS‐induced lipid peroxidation in NSCLC cells
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DOI: 10.1002/2211-5463.13393
Abstract: Ferroptosis is type of programmed cell death, which is known to be involved in certain cancers. Notch3 signaling is reported to be involved in the tumorigenesis of non‐small‐cell lung cancer (NSCLC) and regulates iron metabolism,… read more here.
Keywords: nsclc cells; lipid peroxidation; nsclc; regulates ferroptosis ... See more keywords
Estrogen‐related receptor alpha triggers the proliferation and migration of human non‐small cell lung cancer via interleukin‐6
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DOI: 10.1002/cbf.3337
Abstract: Human non‐small cell lung cancer (NSCLC) is one of the leading causes of cancer deaths worldwide. Estrogenic signals have been suggested to be important for the growth and metastasis of NSCLC cells. Our present data… read more here.
Keywords: nsclc cells; migration; non small; cancer ... See more keywords
MicroRNA‐1 overexpression increases chemosensitivity of non‐small cell lung cancer cells by inhibiting autophagy related 3‐mediated autophagy
Sign Up to like & getrecommendations! Published in 2018 at "Cell Biology International"
DOI: 10.1002/cbin.10995
Abstract: Non‐small cell lung cancer (NSCLC) is a major type of lung cancer. Drug resistance is a enormous obstacle for cancer treatment. Copious microRNAs (miRNAs) have been demonstrated to be implicated in drug resistance in NSCLC.… read more here.
Keywords: overexpression; nsclc cells; ddp resistant; cancer ... See more keywords
Exosomes derived from mesenchymal non‐small cell lung cancer cells promote chemoresistance
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DOI: 10.1002/ijc.30752
Abstract: Non‐small cell lung cancer (NSCLC) is the most common lung cancer type and the most common cause of mortality in lung cancer patients. NSCLC is often associated with resistance to chemotherapeutics and together with rapid… read more here.
Keywords: chemoresistance; exosomes derived; nsclc cells; lung cancer ... See more keywords
2‐Methoxy‐5((3,4,5‐trimethosyphenyl) seleninyl) phenol causes G2/M cell cycle arrest and apoptosis in NSCLC cells through mitochondrial apoptotic pathway and MDM2 inhibition
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23066
Abstract: Nonsmall cell lung cancer (NSCLC) is one of the most common malignancies and needs novel and effective chemotherapy. In this study, our purpose is to explore the anticancer effects of 2‐methoxy‐5((3,4,5‐trimethosyphenyl) seleninyl) phenol (SQ) on… read more here.
Keywords: apoptosis; nsclc cells; seleninyl phenol; methoxy trimethosyphenyl ... See more keywords
Impaired DNA double‐strand breaks repair by kinesin family member 4A inhibition renders human H1299 non‐small‐cell lung cancer cells sensitive to cisplatin
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27703
Abstract: Patients with non‐small‐cell lung cancer (NSCLC) are routinely treated with the platinum‐based chemotherapeutics such as cisplatin. The drug exerts anticancer effects via multiple mechanisms, including DNA double‐strand breaks (DSBs). Enhanced DNA DSB repair capacity would… read more here.
Keywords: cisplatin; nsclc cells; non small; small cell ... See more keywords
circ_0008797 attenuates non-small cell lung cancer proliferation, metastasis, and aerobic glycolysis by sponging miR-301a-3p/SOCS2.
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DOI: 10.1002/tox.23518
Abstract: PURPOSE This paper firstly reported the exact function of circ_0008797 on non-small cell lung cancer (NSCLC) progression. METHODS NSCLC tissues/matched normal tissues were harvested from 88 NSCLC patients. RNA fluorescence in situ hybridization experiment was… read more here.
Keywords: lung; circ; mir 301a; nsclc cells ... See more keywords
FOXC2 promotes epithelial–mesenchymal transition and cisplatin resistance of non-small cell lung cancer cells
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DOI: 10.1007/s00280-018-3697-2
Abstract: PurposePlatinum-based drugs, particularly cisplatin (DDP), are used in the treatment of non-small cell lung cancer (NSCLC). However, development of drug resistance remains the major therapeutic barrier in NSCLC.MethodsThe potential cisplatin resistance-related genes were identified from… read more here.
Keywords: cisplatin; nsclc cells; resistance; non small ... See more keywords
Self-targeted knockdown of CD44 improves cisplatin sensitivity of chemoresistant non-small cell lung cancer cells
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DOI: 10.1007/s00280-018-3737-y
Abstract: BackgroundChemoresistance remains a major challenge for effective chemotherapy of non-small-cell lung carcinoma (NSCLC). CD44 expression is related to the susceptibility of various cancer cell types to anticancer drugs. Here, we systematically investigated the CD44-dependent chemoresistance… read more here.
Keywords: self targeted; nsclc cells; cd44; cell ... See more keywords
CircMIIP Contributes to Non-Small Cell Lung Cancer Progression by Binding miR-766-5p to Upregulate FAM83A Expression
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DOI: 10.1007/s00408-021-00500-3
Abstract: Circular RNA migration and invasion inhibitory protein (circMIIP) is reported to be upregulated in non-small cell lung cancer (NSCLC) tissues compared with normal tissues. However, the role and working mechanism of circMIIP in NSCLC progression… read more here.
Keywords: lung; nsclc cells; cell; fam83a ... See more keywords
Mechanism of miR-455–3 in suppressing epithelial–mesenchymal transition and angiogenesis of non-small cell lung cancer cells
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DOI: 10.1007/s12192-022-01254-4
Abstract: The tumor-suppressing role of miR-455-3p has been reported in lung cancer, but the working mechanism remains to be fully elucidated. This study aims to explore the possible mechanism of miR-455-3p in regulating epithelial–mesenchymal transition (EMT)… read more here.
Keywords: hsf1; gls1; angiogenesis; nsclc cells ... See more keywords