Crizotinib efficacy and safety in patients with advanced NSCLC harboring MET alterations: A real-life data of Turkish Oncology Group
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DOI: 10.1097/md.0000000000032368
Abstract: Crizotinib is a multikinase inhibitor, effective in non-small cell lung cancer (NSCLC) harboring mesenchymal-epidermal transition (MET) alterations. Although small prospective studies showed efficacy and safety of crizotinib in NSCLC with MET alterations, there is limited… read more here.
Keywords: oncology; met alterations; real life; nsclc harboring ... See more keywords
Abstract CT126: An open-label, first-in-human study of BAY2927088 in patients with advanced non-small cell lung cancer (NSCLC) harboring an EGFR and/or HER2 mutation
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DOI: 10.1158/1538-7445.am2023-ct126
Abstract: Background: Despite targeted agents recently approved for treating patients with advanced NSCLC harboring EGFR exon 20 insertion (ex20ins) mutations, there is still a high unmet need for more effective agents with good tolerability. BAY2927088 is… read more here.
Keywords: nsclc harboring; patients advanced; bay2927088; egfr her2 ... See more keywords
Antitumor activity of osimertinib in NSCLC harboring EGFR exon 20 insertions.
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DOI: 10.1200/jco.2017.35.15_suppl.9030
Abstract: 9030Background: EGFR exon 20 insertions (Ex20Ins), the 3rd most common EGFR activating mutation, are generally unresponsive to 1st and 2nd generation EGFR-TKIs. Development of EGFR-TKIs that effectively target NSCLC with Ex20Ins mutations represents a major… read more here.
Keywords: egfr; egfr exon; harboring egfr; exon insertions ... See more keywords
Systemic Therapy for Oligoprogression in Patients with Metastatic NSCLC Harboring Activating EGFR Mutations
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DOI: 10.3390/cancers14030832
Abstract: Simple Summary The oligoprogression concept is characterized by a limited number and/or sites of metastases in which a disease progression appears, and a more indolent tumor biology, raised specifically for oncogene addicted non-small cell lung… read more here.
Keywords: nsclc harboring; egfr mutations; oligoprogression; biology ... See more keywords