Enhancement of Mitochondrial Function by the Neurogenic Molecule NSI-189 Accompanies Reversal of Peripheral Neuropathy and Memory Impairment in a Rat Model of Type 2 Diabetes
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DOI: 10.1155/2022/8566970
Abstract: Aims Mitochondrial dysfunction contributes to many forms of peripheral and central nervous system degeneration. Therapies that protect mitochondrial number and function have the potential to impact the progression of conditions such as diabetic neuropathy. We… read more here.
Keywords: nsi 189; function; mitochondrial function; model type ... See more keywords
Remediation of Radiation-Induced Cognitive Dysfunction through Oral Administration of the Neuroprotective Compound NSI-189
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DOI: 10.1667/rr14879.1
Abstract: Clinical management of primary and secondary central nervous system (CNS) malignancies frequently includes radiotherapy to forestall tumor growth and recurrence after surgical resection. While cranial radiotherapy remains beneficial, adult and pediatric brain tumor survivors suffer… read more here.
Keywords: radiation induced; induced cognitive; cognitive dysfunction; compound ... See more keywords