Articles with "nsp14 nsp10" as a keyword



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Reconstitution and functional characterization of SARS-CoV-2 proofreading complex

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Published in 2021 at "Protein Expression and Purification"

DOI: 10.1016/j.pep.2021.105894

Abstract: The novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2 or COVID-19) has led to a world-wild pandemic. The replication of SARS-CoV-2 RNA genome involves the core replication-transcription complex (RTC, nsp12-nsp7-nsp8) and the proofreading complex (nsp14-nsp10)… read more here.

Keywords: reconstitution functional; proofreading complex; sars cov; cov nsp14 ... See more keywords
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Characterization of the SARS-CoV-2 ExoN (nsp14ExoN–nsp10) complex: implications for its role in viral genome stability and inhibitor identification

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Published in 2022 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkab1303

Abstract: Abstract The SARS-CoV-2 coronavirus is the causal agent of the current global pandemic. SARS-CoV-2 belongs to an order, Nidovirales, with very large RNA genomes. It is proposed that the fidelity of coronavirus (CoV) genome replication… read more here.

Keywords: nsp10 complex; sars cov; viral genome; inhibitor ... See more keywords