SARS-CoV-2 nsp5 Exhibits Stronger Catalytic Activity and Interferon Antagonism than Its SARS-CoV Ortholog
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DOI: 10.1128/jvi.00037-22
Abstract: The nsp5-encoded 3C-like protease is the main coronavirus protease, playing a vital role in viral replication and immune evasion by cleaving viral polyproteins and host immune-related molecules. We showed that both SARS-CoV-2 nsp5 and SARS-CoV… read more here.
Keywords: catalytic activity; nsp5 sars; antagonism sars; sars cov ... See more keywords