An in vitro developmental neurotoxicity screening assay for retinoic acid-induced neuronal differentiation using the human NT2/D1 cell line.
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DOI: 10.1016/j.neuro.2019.04.005
Abstract: Traditional approaches (e.g., neurobehavior, neuropathology) can detect alterations in apical endpoints indicative of developmental neurotoxicity (DNT). However, there is an increasing desire to understand mode-of-action (MOA) for DNT effects; thus, this short communication describes initial… read more here.
Keywords: differentiation; retinoic acid; developmental neurotoxicity; nt2 cell ... See more keywords