cGAS and CD-NTase enzymes: structure, mechanism, and evolution
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DOI: 10.1016/j.sbi.2019.08.003
Abstract: Cyclic GMP–AMP synthase (cGAS) is a signaling enzyme in human cells that controls immune-sensing of cytosolic DNA. The recent discoveries of diverse structural homologs of cGAS in animals and bacteria reveal that cGAS-like signaling is… read more here.
Keywords: cgas; structure mechanism; enzymes structure; biology ... See more keywords