Limited Accuracy of Pan-Trk Immunohistochemistry Screening for NTRK Rearrangements in Follicular-Derived Thyroid Carcinoma
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DOI: 10.3390/ijms23137470
Abstract: Patients with advanced thyroid cancer harboring NTRK rearrangements can be treated with highly effective selective inhibitors. Immunohistochemistry (IHC) analysis, to detect Trk protein expression, represents an appealing screening strategy for NTRK rearrangements, but its efficacy… read more here.
Keywords: ntrk rearrangements; derived thyroid; thyroid cancer; sensitivity specificity ... See more keywords