Abstract 970: Transforming NTRK2 and NTRK3 mutations as potential drivers of leukemia
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DOI: 10.1158/1538-7445.am2018-970
Abstract: The neurotrophic tyrosine receptor kinases (NTRKs) are a family of neuronal transmembrane receptors that signal through several pathways including JAK/STAT, PI3K/AKT, and MEK/ERK to promote proliferation, differentiation, and survival. Although much of the literature has… read more here.
Keywords: ntrk3 mutations; ntrk2 ntrk3; mutations potential; potential drivers ... See more keywords