Abstract 5797: NTX301, a novel DNA hypomethylating agent, targets lipid metabolism in ovarian cancer
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DOI: 10.1158/1538-7445.am2023-5797
Abstract: Background: DNA methylation causes the silencing of tumor suppressor and differentiation-associated genes being linked to chemoresistance and stemness. Previous studies demonstrated that hypomethylating agents (HMA) re-sensitize ovarian cancer (OC) cells to chemotherapy, however, translation to… read more here.
Keywords: ovarian cancer; ntx301 novel; ntx301; novel dna ... See more keywords