Biochemical Characterization of the TINTIN Module of the NuA4 Complex Reveals Allosteric Regulation of Nucleosome Interaction
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DOI: 10.1128/mcb.00170-22
Abstract: Trimer Independent of NuA4 involved in Transcription Interactions with Nucleosomes (TINTIN) is an integral module of the essential yeast lysine acetyltransferase complex NuA4 that plays key roles in transcription regulation and DNA repair. Composed of… read more here.
Keywords: nua4; transcription; tintin; regulation ... See more keywords
Molecular Architecture of the Essential Yeast Histone Acetyltransferase Complex NuA4 Redefines Its Multimodularity
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DOI: 10.1128/mcb.00570-17
Abstract: ABSTRACT Conserved from yeast to humans, the NuA4 histone acetyltransferase is a large multisubunit complex essential for cell viability through the regulation of gene expression, genome maintenance, metabolism, and cell fate during development and stress.… read more here.
Keywords: histone acetyltransferase; architecture; nua4; molecular architecture ... See more keywords