Glucose, amino acids and fatty acids directly regulate ghrelin and NUCB2/nesfatin-1 in the intestine and hepatopancreas of goldfish (Carassius auratus) in vitro.
Sign Up to like & getrecommendations! Published in 2017 at "Comparative biochemistry and physiology. Part A, Molecular & integrative physiology"
DOI: 10.1016/j.cbpa.2017.01.006
Abstract: Ghrelin and nesfatin-1 are two peptidyl hormones primarily involved in food intake regulation. We previously reported that the amount of dietary carbohydrates, protein and lipids modulates the expression of these peptides in goldfish in vivo.… read more here.
Keywords: nesfatin intestine; ghrelin nucb2; physiology; nucb2 nesfatin ... See more keywords
NUCB2/nesfatin-1 – Inhibitory effects on food intake, body weight and metabolism
Sign Up to like & getrecommendations! Published in 2020 at "Peptides"
DOI: 10.1016/j.peptides.2020.170308
Abstract: Since its discovery in 2006 by Oh-I and colleagues, NUCB2/nesfatin-1 encoded by nucleobindin-2 (NUCB2) has drawn sustained attention as reflected in over 500 publications. Among those, more than half focused on the alterations of food… read more here.
Keywords: intake body; food intake; nucb2 nesfatin; body weight ... See more keywords
Alterations of circulating NUCB2/nesfatin-1 during short term therapeutic improvement of anxiety in obese inpatients
Sign Up to like & getrecommendations! Published in 2017 at "Psychoneuroendocrinology"
DOI: 10.1016/j.psyneuen.2017.02.021
Abstract: In addition to its anorexigenic properties in the neuroendocrine regulation of hunger and satiety, mounting evidence indicates a role for NUCB2/nesfatin-1 in the regulation of emotional stress responses which seems to occur in a sex-specific… read more here.
Keywords: anxiety; treatment; nucb2 nesfatin; improvement anxiety ... See more keywords
NUCB2/nesfatin-1 suppresses the acrosome reaction in sperm within the mouse epididymis
Sign Up to like & getrecommendations! Published in 2023 at "Animal Cells and Systems"
DOI: 10.1080/19768354.2023.2212741
Abstract: ABSTRACT Nesfatin-1, a polypeptide hormone derived from the nucleobindin 2 (NUCB2) precursor protein, is known to regulate appetite and energy metabolism. Recent studies have also shown that NUCB2/nesfatin-1 is expressed in the reproductive organs of… read more here.
Keywords: mouse epididymis; acrosome reaction; nucb2; nucb2 nesfatin ... See more keywords
Nucleobindin‐2/nesfatin‐1 enhances the cell proliferation, migration, invasion and epithelial‐mesenchymal transition in gastric carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17522
Abstract: Nesfatin‐1, a newly discovered adipokine derived from nucleobindin‐2 (NUCB2), has been described as a new prognostic marker in cancers. This study aimed to explore the functional role of NUCB2/nesfatin‐1 in the cell proliferation, migration and… read more here.
Keywords: migration invasion; proliferation migration; nucb2 nesfatin;
NUCB2/Nesfatin-1 Regulation of Chronic Visceral Hyperalgesia
Sign Up to like & getrecommendations! Published in 2022 at "Applied Bionics and Biomechanics"
DOI: 10.1155/2022/4079533
Abstract: Objective We previously described that different concentration Nucleobindin-2 (NUCB2)/Nesfatin-1 gradients differently regulated visceral hypersensitivity in irritable bowel syndrome. Therefore, this study is aimed at evaluating the effect of NUCB2/Nesfatin-1 on model rats with chronic visceral… read more here.
Keywords: chronic visceral; visceral hyperalgesia; group; intervention ... See more keywords
Pharmacological inhibition of cannabinoid receptor 1 stimulates gastric release of nesfatin-1 via the mTOR pathway
Sign Up to like & getrecommendations! Published in 2017 at "World Journal of Gastroenterology"
DOI: 10.3748/wjg.v23.i35.6403
Abstract: AIM To determine whether Nucb2/nesfatin1 production is regulated by the cannabinoid system through the intracellular mTOR pathway in the stomach. METHODS Sprague Dawley rats were treated with vehicle, rimonabant, rapamycin or rapamycin+rimonabant. Gastric tissue obtained… read more here.
Keywords: mtor pathway; inhibition cannabinoid; cannabinoid receptor; mtor ... See more keywords