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Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-04005-z
Abstract: Symplekin is a multifunctional protein that localizes to both tight junctions and the nucleus in polarized epithelial cells, with confirmed roles in mRNA maturation, transcriptional modulation and tight-junction assembly. However, the mechanisms governing its subcellular…
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Keywords:
symplekin;
accumulation;
nuclear symplekin;
proliferation dedifferentiation ... See more keywords
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Published in 2018 at "Science Advances"
DOI: 10.1126/sciadv.aat6224
Abstract: MET-2/SETDB1 and interactors LIN-65/ATF7IP and ARLE-14/ARL14EP initiate heterochromatin formation during embryogenesis. Heterochromatin formation during early embryogenesis is timed precisely, but how this process is regulated remains elusive. We report the discovery of a histone methyltransferase…
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Keywords:
histone methyltransferase;
nuclear accumulation;
heterochromatin formation;
formation ... See more keywords
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Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2592
Abstract: Background: Fibroblast growth factor receptor 4 (FGFR4) is a member of the transmembrane tyrosine kinase receptor family and has been linked to a variety of malignancies. NRF2 (Nuclear factor-erythroid 2-related factor) is a cytoprotective factor…
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Keywords:
nuclear accumulation;
fgfr4;
accumulation nrf2;
accumulation ... See more keywords
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Published in 2018 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2018.00617
Abstract: The purpose of this study was to investigate the nuclear accumulation of heat shock protein 70 (HSP70), a molecular chaperonin in mouse skeletal muscle in response to aging, heat stress, and hindlimb unloading with or…
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Keywords:
accumulation;
hsp70;
accumulation hsp70;
response ... See more keywords