Articles with "nuclear antigen" as a keyword



Molecular characterization and expression profile of an alternate proliferating cell nuclear antigen homolog PbPCNA2 in Plasmodium berghei

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Published in 2019 at "IUBMB Life"

DOI: 10.1002/iub.2036

Abstract: Proliferative cell nuclear antigen (PCNA) is the processivity factor for various DNA polymerases and it functions in response to DNA damage in eukaryotic system. Plasmodium falciparum contains two PCNAs, while PCNA1 has been attributed to… read more here.

Keywords: cell nuclear; pbpcna2; physiology; expression ... See more keywords

Use of antibodies against Epstein–Barr virus nuclear antigen 1 for detection of cellular proteins with monomethylated arginine residues that are potentially involved in viral transformation

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Published in 2024 at "Archives of Virology"

DOI: 10.1007/s00705-024-06172-7

Abstract: Epstein–Barr virus nuclear antigen 1 (EBNA1) contains two arginine-glycine (RG) repeats that contain symmetric/asymmetric dimethylarginine (SDMA/ADMA) and monomethylarginine (MMA) residues. We generated mouse monoclonal antibodies directed against a monomethylated GRGRGG-containing repeat located between amino acids… read more here.

Keywords: nuclear antigen; epstein barr; cellular proteins; virus nuclear ... See more keywords

Assessment of proliferating cell nuclear antigen (PCNA) expression at the invading front of oral squamous cell carcinoma

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Published in 2019 at "BMC Oral Health"

DOI: 10.1186/s12903-019-0928-9

Abstract: BackgroundAccurate prediction of the behaviour of oral squamous cell carcinoma (OSCC) is necessary to determine prognosis and provide appropriate treatment. Therefore, it is important to investigate potential prognostic markers to determine their predictive ability. Histological… read more here.

Keywords: cell; cell nuclear; proliferating cell; nuclear antigen ... See more keywords
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Kaposi’s sarcoma-associated herpesvirus latency-associated nuclear antigen dysregulates expression of MCL-1 by targeting FBW7

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Published in 2021 at "PLoS Pathogens"

DOI: 10.1371/journal.ppat.1009179

Abstract: Primary effusion lymphoma (PEL) is an aggressive B cell lymphoma that is etiologically linked to Kaposi’s sarcoma-associated herpesvirus (KSHV). Despite standard multi-chemotherapy treatment, PEL continues to cause high mortality. Thus, new strategies to control PEL… read more here.

Keywords: associated nuclear; kaposi sarcoma; latency associated; nuclear antigen ... See more keywords

Impact of Epstein–Barr Virus Nuclear Antigen 1 on Neuroinflammation in PARK2 Knockout Mice

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Published in 2024 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms251910697

Abstract: This study aimed to explore the intricate relationship between mitochondrial dysfunction, infection, and neuroinflammation, focusing specifically on the impact of pathogenic epitopes of the Epstein–Barr Virus (EBV) nuclear antigen 1 (EBNA1) in a mouse model… read more here.

Keywords: mice; nuclear antigen; epstein barr; ebna1386 405 ... See more keywords

Berberine inhibits the proliferation of human nasopharyngeal carcinoma cells via an Epstein-Barr virus nuclear antigen 1-dependent mechanism.

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Published in 2017 at "Oncology reports"

DOI: 10.3892/or.2017.5489

Abstract: Nasopharyngeal carcinoma (NPC) is a malignancy derived from the epithelial cells of the nasopharynx cavity, and is closely associated with Epstein-Barr virus (EBV) infection. In addition to NPC, EBV causes various human malignancies, such as gastric cancer,… read more here.

Keywords: epstein barr; barr virus; nuclear antigen; nasopharyngeal carcinoma ... See more keywords

The Effects of Epstein-Barr Virus Nuclear Antigen 2 (EBNA2) on B-Lymphocytic Activity.

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Published in 2018 at "Clinical laboratory"

DOI: 10.7754/clin.lab.2017.170812

Abstract: BACKGROUND Epstein-Barr virus is a worldwide disease that can cause a wide range of human diseases, the person will become a lifelong carrier of the virus once infected. To investigate the mechanism of Epstein-Barr virus… read more here.

Keywords: epstein barr; barr virus; nuclear antigen; virus ... See more keywords