Unraveling docking and initiation of mRNA export through the nuclear pore complex
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DOI: 10.1002/bies.202200027
Abstract: The nuclear export of mRNA through the nuclear pore complex (NPC) is a process required for the healthy functioning of human cells, making it a critical area of research. However, the geometries of mRNA and… read more here.
Keywords: nuclear pore; pore complex; nuclear basket; microscopy ... See more keywords
ZC3HC1 is a structural element of the nuclear basket effecting interlinkage of TPR polypeptides
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DOI: 10.1091/mbc.e22-02-0037
Abstract: The nuclear basket (NB), anchored to the nuclear pore complex (NPC), is commonly thought of as built solely of protein TPR polypeptides, the latter thus regarded as the NB’s only scaffold-forming components. In the current… read more here.
Keywords: nuclear basket; zc3hc1; tpr; structural element ... See more keywords
Abstract MP145: Potential Functions of the Nuclear Basket Associated With Dilated Cardiomyopathy
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DOI: 10.1161/res.127.suppl_1.mp145
Abstract: Objectives: NUP153 overexpression is clinically correlated with cardiomyopathies, specifically dilated cardiomyopathy (DCM). In combination with the nuclear pore complex (NPC) proteins TPR and NUP50, all three form the basket structure of the NPC that sits… read more here.
Keywords: analysis; nuclear basket; abstract mp145; dilated cardiomyopathy ... See more keywords