Nuclear-capture of endosomes depletes nuclear G-actin to promote SRF/MRTF activation and cancer cell invasion.
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DOI: 10.1038/s41467-021-26839-y
Abstract: Signals are relayed from receptor tyrosine kinases (RTKs) at the cell surface to effector systems in the cytoplasm and nucleus, and coordination of this process is important for the execution of migratory phenotypes, such as… read more here.
Keywords: nuclear capture; invasion; capture endosomes; nuclear actin ... See more keywords