Prognostic significance of Daxx NCR (Nuclear/Cytoplasmic Ratio) in gastric cancer
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Medicine"
DOI: 10.1002/cam4.1144
Abstract: In addition to regulating apoptosis via its interaction with the death domain of Fas receptor, death domain associated protein 6 (Daxx) is also known to be involved in transcriptional regulation, suggesting that the function of… read more here.
Keywords: risk; daxx; nuclear cytoplasmic; ratio ... See more keywords
YAP nuclear‐cytoplasmic translocation is regulated by mechanical signaling, protein modification, and metabolism
Sign Up to like & getrecommendations! Published in 2020 at "Cell Biology International"
DOI: 10.1002/cbin.11345
Abstract: Nuclear‐cytoplasmic transport is necessary for the biological function of nuclear proteins. The mechanism underlying this process is very complex and has been a subject of intense research. Yes‐associated protein (YAP), a Hippo signaling pathway effector,… read more here.
Keywords: protein; signaling protein; nuclear cytoplasmic; protein modification ... See more keywords
Visualization of Nuclear and Cytoplasmic Long Noncoding RNAs at Single-Cell Level by RNA-FISH.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0664-3_15
Abstract: The RNA fluorescence in situ hybridization (RNA-FISH) methodology offers an attractive strategy to deepen our knowledge on the long noncoding RNA biology. In this chapter, we provide a comprehensive overview of the current RNA-FISH protocols… read more here.
Keywords: long noncoding; methodology; rna fish; nuclear cytoplasmic ... See more keywords
Nuclear/Cytoplasmic Fractionation to Study Hippo Effectors.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8910-2_10
Abstract: The translocation or shuttling of Hippo proteins between the nucleus and cytoplasm is a rapid event following cytoskeletal or mechanical cues as well as stimulation with extracellular growth factors. Here we describe an experimental procedure… read more here.
Keywords: study hippo; fractionation study; hippo effectors; nuclear cytoplasmic ... See more keywords
The interplay between nuclear and cytoplasmic distribution of methionine cycle enzymes in acute liver injury
Sign Up to like & getrecommendations! Published in 2017 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2017.04.275
Abstract: The hepatic methionine cycle comprises specific isoenzymes and proteins classically ascribed to the cytoplasm, with metabolites being putatively transported to other subcellular locations as required. This hypothesis was challenged by the identification of several enzymes… read more here.
Keywords: nuclear cytoplasmic; acute liver; cycle; methionine cycle ... See more keywords
Cytological interpretation of p16 immunohistochemistry in head and neck carcinomas: does the choice of fixative matter?
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Society of Cytopathology"
DOI: 10.1016/j.jasc.2020.09.012
Abstract: INTRODUCTION Fine-needle aspiration (FNA) of nodal metastases plays a key role in the diagnosis of oropharyngeal squamous cell carcinoma (OPSCC). Because of significant clinical implications of human papillomavirus (HPV)-related OPSCC, immunohistochemistry for p16 as a… read more here.
Keywords: p16; immunohistochemistry; ccb; cytoplasmic staining ... See more keywords
The Tau of Nuclear-Cytoplasmic Transport
Sign Up to like & getrecommendations! Published in 2018 at "Neuron"
DOI: 10.1016/j.neuron.2018.08.026
Abstract: Aggregation of microtubule-associated protein tau is the hallmark of tauopathies, including Alzheimer's disease. Eftekharzadeh et al. (2018) demonstrate that pathogenic tau alters nucleocytoplasmic transport by interacting with components of the nuclear pore complex, revealing a perturbation… read more here.
Keywords: tau; nuclear cytoplasmic; transport; tau nuclear ... See more keywords
Nuclear and Cytoplasmic Functions of Vitamin C
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Research in Toxicology"
DOI: 10.1021/acs.chemrestox.0c00348
Abstract: Vitamin C (ascorbic acid) is a water-soluble antioxidant and a cofactor for a large number of enzymes. It is present in all tissues and especially abundant in corneal epithelium, stem cells, and neurons. Although similar… read more here.
Keywords: nuclear cytoplasmic; functions vitamin; cytoplasmic functions; activity ... See more keywords
Nuclear and cytoplasmic WDR-23 isoforms mediate differential effects on GEN-1 and SKN-1 substrates
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-48286-y
Abstract: Maintaining a healthy cellular environment requires the constant control of proteostasis. E3 ubiquitin ligase complexes facilitate the post-translational addition of ubiquitin, which based on the quantity and specific lysine linkages, results in different outcomes. Our… read more here.
Keywords: wdr 23b; nuclear cytoplasmic; cytoplasmic wdr; wdr ... See more keywords
SPINDLY O-fucosylates nuclear and cytoplasmic proteins involved in diverse cellular processes in plants.
Sign Up to like & getrecommendations! Published in 2023 at "Plant physiology"
DOI: 10.1093/plphys/kiad011
Abstract: SPINDLY (SPY) is a novel nucleocytoplasmic protein O-fucosyltransferase that regulates target protein activity or stability via O-fucosylation of specific Ser/Thr residues. Previous genetic studies indicate that AtSPY regulates plant development during vegetative and reproductive growth… read more here.
Keywords: diverse cellular; spindly fucosylates; fucosylates nuclear; cytoplasmic proteins ... See more keywords
Subcellular analysis of nuclear and cytoplasmic redox indices differentiates breast cancer cell subtypes better than nuclear-to-cytoplasmic area ratio
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biomedical Optics"
DOI: 10.1117/1.jbo.27.8.086001
Abstract: Abstract. Significance: Stratification of malignancy is valuable for cancer treatment. Both optical redox imaging (ORI) indices and nuclear-to-cytoplasmic volume/area ratio (N:C ratio) have been investigated to differentiate between cancers with varying aggressiveness, but these two… read more here.
Keywords: cell; ori indices; area ratio; nuclear cytoplasmic ... See more keywords