Myeloid cell nuclear differentiation antigen controls the pathogen-stimulated type I interferon cascade in human monocytes by transcriptional regulation of IRF7
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DOI: 10.1038/s41467-021-27701-x
Abstract: Type I interferons (IFNs) are critical for anti-viral responses, and also drive autoimmunity when dysregulated. Upon viral sensing, monocytes elicit a sequential cascade of IFNβ and IFNα production involving feedback amplification, but how exactly this… read more here.
Keywords: ifn; cell nuclear; nuclear differentiation; interferon ... See more keywords