A key role of nuclear factor Y in the refeeding response of fatty acid synthase in adipocytes
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Letters"
DOI: 10.1002/1873-3468.12620
Abstract: Fatty acid synthase (Fasn) is a key component of energy metabolism that is dynamically induced by food intake. Although extensive studies have revealed a number of transcription factors involved in the fasting/refeeding transition of Fasn… read more here.
Keywords: acid synthase; fatty acid; nuclear factor; refeeding response ... See more keywords
Metformin inhibits pro‐inflammatory responses via targeting nuclear factor‐κB in HaCaT cells
Sign Up to like & getrecommendations! Published in 2019 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3367
Abstract: Psoriasis is a prevalent, chronic inflammatory skin disease that arises from rapid and excessive growth of keratinocytes induced by abnormal inflammatory responses. Metformin is the first‐line drug in type 2 diabetes and has been proven… read more here.
Keywords: inflammatory responses; metformin inhibits; hacat cells; factor ... See more keywords
N,N‐Diarylsulfonamide Reduces Proinflammatory Cytokine Interleukin‐6 Levels in Cells through Nuclear Factor‐κB Regulation
Sign Up to like & getrecommendations! Published in 2024 at "ChemMedChem"
DOI: 10.1002/cmdc.202300598
Abstract: The arylsulfonamides were synthesized from aryl sulfonyl chloride and aromatic amines in dichloromethane in the presence of pyridine. The aryne chemistry was used to prepare diarylsulfonamide from arylsulfonamides and O‐silylaryl triflate with CsF in acetonitrile… read more here.
Keywords: diarylsulfonamide reduces; reduces proinflammatory; nuclear factor; proinflammatory cytokine ... See more keywords
Nuclear factor I X is a recurrent target for HPV16 insertions in anal carcinomas
Sign Up to like & getrecommendations! Published in 2018 at "Genes"
DOI: 10.1002/gcc.22675
Abstract: Anal carcinomas (AC) are associated with human papillomavirus (HPV) DNA sequences, but little is known about the physical state of the viral genome in carcinoma cells. To define the integration status and gene(s) targeted by… read more here.
Keywords: integration; anal carcinomas; hpv; gene ... See more keywords
Down‐regulation of hepatocyte nuclear factor‐4α and defective zonation in livers expressing mutant Z α1‐antitrypsin
Sign Up to like & getrecommendations! Published in 2017 at "Hepatology"
DOI: 10.1002/hep.29160
Abstract: α1‐Antitrypsin (AAT) deficiency is one of the most common genetic disorders and the liver disease due to the Z mutant of AAT (ATZ) is a prototype of conformational disorder due to protein misfolding with consequent… read more here.
Keywords: hepatocyte nuclear; nuclear factor; zonation livers; hepatology ... See more keywords
Galangin attenuates cadmium‐evoked nephrotoxicity: Targeting nucleotide‐binding domain‐like receptor pyrin domain containing 3 inflammasome, nuclear factor erythroid 2‐related factor 2, and nuclear factor kappa B signaling
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23059
Abstract: The kidney is highly vulnerable to cadmium‐evoked oxidative injury. Galangin is a natural flavone with reported antioxidant properties. This study investigated the potential modulating activity of galangin against cadmium‐induced nephrotoxicity and explored the underlining mechanisms.… read more here.
Keywords: nuclear factor; galangin; cadmium evoked; factor ... See more keywords
Nesfatin‐1 alleviates hyperoxia‐induced bronchopulmonary dysplasia (BPD) via the nuclear factor‐κB (NF‐κB) p65 signaling pathway
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23680
Abstract: Bronchopulmonary dysplasia (BPD) is a chronic respiratory disease in newborns, which severely influences the health of infants and lacks effective clinical treatment strategies. The pathogenesis of BPD is correlated to enhanced inflammation and activated oxidative… read more here.
Keywords: dysplasia bpd; bronchopulmonary dysplasia; bpd; nuclear factor ... See more keywords
Inhibitory effects of biochanin A on titanium particle‐induced osteoclast activation and inflammatory bone resorption via NF‐κB and MAPK pathways
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29948
Abstract: Revision operations have become a new issue after successful artificial joint replacements, and periprosthetic osteolysis leading to prosthetic loosening is the main cause of why the overactivation of osteoclasts (OCs) plays an important role. The… read more here.
Keywords: inhibitory effects; inflammatory; resorption; factor ... See more keywords
SN‐38, an active metabolite of irinotecan, inhibits transcription of nuclear factor erythroid 2‐related factor 2 and enhances drug sensitivity of colorectal cancer cells
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23685
Abstract: Nuclear factor erythroid 2‐related factor 2 (Nrf2) significantly contributes to drug resistance of cancer cells, and Nrf2 inhibitors have been vigorously pursued. Repurposing of existing drugs, especially anticancer drugs, is a straightforward and promising strategy… read more here.
Keywords: cancer cells; factor erythroid; drug; factor ... See more keywords
Paeonol ameliorates monosodium urate‐induced arthritis in rats through inhibiting nuclear factor‐κB‐mediated proinflammatory cytokine production
Sign Up to like & getrecommendations! Published in 2019 at "Phytotherapy Research"
DOI: 10.1002/ptr.6472
Abstract: Moutan Cortex has been widely used to treat various types of arthritis in traditional Chinese medicine. Paeonol is isolated as an active ingredient from Moutan Cortex. However, the effect and potential mechanism of paeonol on… read more here.
Keywords: induced arthritis; paeonol; rats inhibiting; mia rats ... See more keywords
Nuclear factor erythroid 2-related factor 2 in human papillomavirus-related cancers.
Sign Up to like & getrecommendations! Published in 2021 at "Reviews in medical virology"
DOI: 10.1002/rmv.2308
Abstract: High-risk human papillomavirus (HR-HPV) infection is a necessary cause for the development of cervical cancer. Moreover, HR-HPV is also associated with cancers in the anus, vagina, vulva, penis and oropharynx. HR-HPVs target and modify the… read more here.
Keywords: factor erythroid; erythroid related; related factor; human papillomavirus ... See more keywords