Articles with "nuclear galectin" as a keyword



Nuclear Galectin-1 promotes KRAS-dependent activation of pancreatic cancer stellate cells

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Published in 2025 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2424051122

Abstract: Significance Our findings provide insights into the biology of pancreatic stellate cell (PSC) activation in pancreatic ductal adenocarcinoma (PDAC), a leading cause of cancer mortality. By identifying a nuclear role for Galectin-1 (Gal1) in regulating… read more here.

Keywords: cancer; stellate; activation; nuclear galectin ... See more keywords