Classification of nuclear morphology in endocytoscopy of colorectal neoplasms.
Sign Up to like & getrecommendations! Published in 2017 at "Gastrointestinal endoscopy"
DOI: 10.1016/j.gie.2016.10.039
Abstract: BACKGROUND AND AIMS We investigated endocytoscopy (EC) findings that were considered risk factors for colorectal neoplasms and determined whether they could be used as new indices to identify carcinomas with massive submucosal invasion (SM-m) or… read more here.
Keywords: classification; accuracy; classification nuclear; predictive value ... See more keywords
Loss of lamin‐B1 and defective nuclear morphology are hallmarks of astrocyte senescence in vitro and in the aging human hippocampus
Sign Up to like & getrecommendations! Published in 2021 at "Aging Cell"
DOI: 10.1111/acel.13521
Abstract: The increase in senescent cells in tissues, including the brain, is a general feature of normal aging and age‐related pathologies. Senescent cells exhibit a specific phenotype, which includes an altered nuclear morphology and transcriptomic changes.… read more here.
Keywords: lamin; senescence vitro; nuclear morphology; senescence ... See more keywords
Nuclear Morphology and the Biology of Cancer Cells
Sign Up to like & getrecommendations! Published in 2020 at "Acta Cytologica"
DOI: 10.1159/000508780
Abstract: Background: For more than a century, diagnostic pathologists have used morphologic abnormalities of the nucleus as essential diagnostic features to distinguish benign from malignant cells. These features include nuclear enlargement and increased nuclear-to-cytoplasmic ratio, nuclear… read more here.
Keywords: malignant cells; nuclear envelope; biology; cancer cells ... See more keywords
Cuplike nuclear morphology in pediatric B-cell acute lymphoblastic leukemia.
Sign Up to like & getrecommendations! Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-05-848788
Abstract: ![Figure][1] A 7-year-old previously healthy girl presented with fever, fatigue, and weight loss for 1 month. Laboratory test revealed normocytic anemia (hemoglobin, 7.1 g/dL), neutropenia (0.17 × 109/L), and 30% small- to medium-sized blasts with… read more here.
Keywords: cell acute; cuplike nuclear; cuplike; morphology pediatric ... See more keywords
Cuplike nuclear morphology is highly associated with IKZF1 deletion in pediatric precursor B-cell ALL.
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood.2019000604
Abstract: TO THE EDITOR: Cuplike nuclei (CLN) (nuclei with prominent invagination) are recognized as a distinctive morphologic finding in the blasts of acute myeloid leukemia (AML).[1][1][⇓][2][⇓][3][⇓][4][⇓][5]-[6][6] They are seen in ∼20% of all AML cases[2][2],[4][4],[5][5] and… read more here.
Keywords: highly associated; associated ikzf1; cuplike nuclear; ikzf1 deletion ... See more keywords
Extreme nuclear branching in healthy epidermal cells of the Xenopus tail fin
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cell Science"
DOI: 10.1242/jcs.217513
Abstract: ABSTRACT Changes in nuclear morphology contribute to the regulation of complex cell properties, including differentiation and tissue elasticity. Perturbations of nuclear morphology are associated with pathologies that include progeria, cancer and muscular dystrophy. The mechanisms… read more here.
Keywords: nuclear morphology; fin; nuclear branching; cells xenopus ... See more keywords
Effects of Myostatin on Nuclear Morphology at the Myotendinous Junction
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24076634
Abstract: Myostatin (Myo) is known to suppress skeletal muscle growth, and was recently reported to control tendon homeostasis. The purpose of the present study was to investigate the regulatory involvement of Myo in the myotendinous junction… read more here.
Keywords: myo; myotendinous junction; mtj; nuclear morphology ... See more keywords
Role of Lamin A and emerin in maintaining nuclear morphology in different subtypes of ovarian epithelial cancer
Sign Up to like & getrecommendations! Published in 2022 at "Oncology Letters"
DOI: 10.3892/ol.2021.13127
Abstract: The nuclear lamina protein, Lamin A and inner nuclear membrane protein, emerin participate in maintaining nuclear morphology. However, their correlations with the nuclear shape in the four representative ovarian epithelial cancer subtypes, high-grade serous carcinoma… read more here.
Keywords: ovarian epithelial; epithelial cancer; morphology; ccca ... See more keywords