Coupling 1D modifications and 3D nuclear organization: data, models and function.
Sign Up to like & getrecommendations! Published in 2017 at "Current opinion in cell biology"
DOI: 10.1016/j.ceb.2016.12.001
Abstract: Over the past decade, advances in molecular methods have strikingly improved the resolution at which nuclear genome folding can be analyzed. This revealed a wealth of conserved features organizing the one dimensional DNA molecule into… read more here.
Keywords: organization data; data models; modifications nuclear; nuclear organization ... See more keywords
Contribution of Immunoglobulin Enhancers to B Cell Nuclear Organization
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.877930
Abstract: B cells undergo genetic rearrangements at immunoglobulin gene (Ig) loci during B cell maturation. First V(D)J recombination occurs during early B cell stages followed by class switch recombination (CSR) and somatic hypermutation (SHM) which occur… read more here.
Keywords: enhancers cell; immunoglobulin enhancers; cell nuclear; nuclear organization ... See more keywords