Quantitative Measurement of Cytosolic and Nuclear Penetration of Oligonucleotide Therapeutics.
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DOI: 10.1021/acschembio.1c00830
Abstract: A major obstacle in the development of effective oligonucleotide therapeutics is a lack of understanding about their cytosolic and nuclear penetration. To address this problem, we have applied the chloroalkane penetration assay (CAPA) to oligonucleotide… read more here.
Keywords: quantitative measurement; penetration; nuclear penetration; cytosolic nuclear ... See more keywords