Genome-Wide Identification of Chromatin Domains Anchored at the Nuclear Periphery in Plants.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8657-6_23
Abstract: As a functional compartment, the nuclear periphery plays critical roles in regulating the spatial organization of chromatin in the nuclei and gene expression. Generally, the nuclear periphery is a transcriptionally repressed compartment enriched for silenced… read more here.
Keywords: genome wide; wide identification; chromatin; nuclear periphery ... See more keywords
Lamins Organize the Global Three-Dimensional Genome from the Nuclear Periphery.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular cell"
DOI: 10.1016/j.molcel.2018.05.017
Abstract: Lamins are structural components of the nuclear lamina (NL) that regulate genome organization and gene expression, but the mechanism remains unclear. Using Hi-C, we show that lamins maintain proper interactions among the topologically associated chromatin… read more here.
Keywords: nuclear periphery; chromatin domains; genome; lamins organize ... See more keywords
Emerin interacts with histone methyltransferases to regulate repressive chromatin at the nuclear periphery
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.1007120
Abstract: X-Linked Emery-Dreifuss muscular dystrophy is caused by mutations in the gene encoding emerin. Emerin is an inner nuclear membrane protein important for repressive chromatin organization at the nuclear periphery. Myogenic differentiation is a tightly regulated… read more here.
Keywords: nuclear periphery; repressive chromatin; emerin; ezh2 g9a ... See more keywords
GIP1 and GIP2 Contribute to the Maintenance of Genome Stability at the Nuclear Periphery
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2021.804928
Abstract: The maintenance of genetic information is important in eukaryotes notably through mechanisms occurring at the nuclear periphery where inner nuclear membrane proteins and nuclear pore-associated components are key factors regulating the DNA damage response (DDR).… read more here.
Keywords: genome stability; nuclear periphery; periphery; gip1 gip2 ... See more keywords