Elevated Nuclear PHGDH Synergistically Functions with cMyc to Reshape the Immune Microenvironment of Liver Cancer.
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DOI: 10.1002/advs.202205818
Abstract: Herein, we observed that nuclear localization of phosphoglycerate dehydrogenase (PHGDH) is associated with poor prognosis in liver cancer, and Phgdh is required for liver cancer progression in a mouse model. Unexpectedly, impairment of Phgdh enzyme… read more here.
Keywords: nuclear phgdh; phgdh; elevated nuclear; liver cancer ... See more keywords