When PIP2 Meets p53: Nuclear Phosphoinositide Signaling in the DNA Damage Response
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DOI: 10.3389/fcell.2022.903994
Abstract: The mechanisms that maintain genome stability are critical for preventing tumor progression. In the past decades, many strategies were developed for cancer treatment to disrupt the DNA repair machinery or alter repair pathway selection. Evidence… read more here.
Keywords: damage; dna damage; nuclear phosphoinositide; nuclear phosphoinositides ... See more keywords
Nuclear Phosphoinositides: Their Regulation and Roles in Nuclear Functions
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DOI: 10.3390/ijms20122991
Abstract: Polyphosphoinositides (PPIns) are a family of seven lipid messengers that regulate a vast array of signalling pathways to control cell proliferation, migration, survival and differentiation. PPIns are differentially present in various sub-cellular compartments and, through… read more here.
Keywords: nuclear phosphoinositides; nuclear functions; phosphoinositides regulation; roles nuclear ... See more keywords