Articles with "nuclear pklr" as a keyword



Abstract 3062: ROMO1 mediates mitochondrial function links to neuroendocrine differentiation of prostate cancer enhancement by the nuclear PKLR/MYCN/MAX complex

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-3062

Abstract: Conventional treatment of prostate cancer (PCa) uses androgen deprivation therapy (ADT) to inhibit androgen receptor (AR) signaling-driven tumor progression. ADT-induced PCa recurrence may progress to AR-negative phenotype with neuroendocrine (NE) features on histology, which is… read more here.

Keywords: pklr; nuclear pklr; romo1; pklr mycn ... See more keywords