Single domain antibodies for the knockdown of cytosolic and nuclear proteins.
Sign Up to like & getrecommendations! Published in 2017 at "Protein Science"
DOI: 10.1002/pro.3154
Abstract: Single domain antibodies (sdAbs) from camels or sharks comprise only the variable heavy chain domain. Human sdAbs comprise the variable domain of the heavy chain (VH) or light chain (VL) and can be selected from… read more here.
Keywords: sdabs; single domain; domain antibodies; cytosolic nuclear ... See more keywords
Changes of Arg-X proteolysis localization under conditions of deacetylation inhibition of nuclear proteins in spring and winter wheat seedlings
Sign Up to like & getrecommendations! Published in 2018 at "Acta Physiologiae Plantarum"
DOI: 10.1007/s11738-018-2652-5
Abstract: The investigation of the nuclear proteins has always been relevant, because they are involved in the expression, replication, storage, reparation and transmission of genetic information. It is known that sodium butyrate, as an inhibitor of… read more here.
Keywords: proteolysis; winter wheat; nuclear proteins; deacetylation inhibition ... See more keywords
Proteomic analysis of S-nitrosylated nuclear proteins in rat cortical neurons
Sign Up to like & getrecommendations! Published in 2018 at "Science Signaling"
DOI: 10.1126/scisignal.aar3396
Abstract: The S-nitrosylated proteome directs dendritogenesis in developing cortical neurons. Discovering the neuronal SNO-ome Posttranslational modifications (PTMs) regulate protein abundance, localization, and function. S-nitrosylation (or “SNO”) is a PTM involving the attachment of a nitric oxide… read more here.
Keywords: nitrosylated nuclear; rat cortical; nitrosylation; nuclear proteins ... See more keywords
Combining affinity purification and mass spectrometry to define the network of the nuclear proteins interacting with the N-terminal region of FMRP
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.954087
Abstract: Fragile X-Syndrome (FXS) represents the most common inherited form of intellectual disability and the leading monogenic cause of Autism Spectrum Disorders. In most cases, this disease results from the absence of expression of the protein… read more here.
Keywords: mass spectrometry; fmrp; affinity purification; nuclear proteins ... See more keywords
Germinal center B cells that acquire nuclear proteins are specifically suppressed by follicular regulatory T cells
Sign Up to like & getrecommendations! Published in 2023 at "eLife"
DOI: 10.7554/elife.83908
Abstract: Follicular regulatory T cells (Tfr) restrict development of autoantibodies and autoimmunity while supporting high-affinity foreign antigen-specific humoral response. However, whether Tfr can directly repress germinal center (GC) B cells that acquire autoantigens is unclear. Moreover,… read more here.
Keywords: regulatory cells; cells acquire; center cells; germinal center ... See more keywords