Mechanisms of RNA export and nuclear retention
Sign Up to like & getrecommendations! Published in 2022 at "Wiley Interdisciplinary Reviews: RNA"
DOI: 10.1002/wrna.1755
Abstract: With the identification of huge amount of noncoding RNAs in recent years, the concept of RNA localization has extended from traditional mRNA export to RNA export of mRNA and ncRNA as well as nuclear retention… read more here.
Keywords: mechanisms rna; nuclear retention; rna export; sequence dependent ... See more keywords
Mechanisms of Long Noncoding RNA Nuclear Retention.
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DOI: 10.1016/j.tibs.2020.07.001
Abstract: Long noncoding RNAs (lncRNAs) are crucial regulators in diverse cellular contexts and biological processes. The subcellular localization of lncRNAs determines their modes of action. Compared to mRNAs, however, many mRNA-like lncRNAs are preferentially localized to… read more here.
Keywords: rna nuclear; long noncoding; noncoding rna; mechanisms long ... See more keywords
Herpes Simplex Virus 1 Expressing GFP-Tagged Virion Host Shutoff (vhs) Protein Uncouples the Activities of RNA Degradation and Differential Nuclear Retention of the Virus Transcriptome
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DOI: 10.1128/jvi.01926-21
Abstract: Like many viruses, herpes simplex virus 1 (HSV1) expresses an endoribonuclease, the virion host shutoff (vhs) protein, which regulates the RNA environment of the infected cell and facilitates the classical cascade of virus protein translation.… read more here.
Keywords: nuclear retention; vhs; degradation; virus ... See more keywords
ZFC3H1 and U1-70K promote the nuclear retention of mRNAs with 5′ splice site motifs within nuclear speckles
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DOI: 10.1261/rna.079104.122
Abstract: Quality control of mRNA represents an important regulatory mechanism for gene expression in eukaryotes. One component of this quality control is the nuclear retention and decay of misprocessed RNAs. Previously, we demonstrated that mature mRNAs… read more here.
Keywords: retention; nuclear retention; nuclear speckles; retention mrnas ... See more keywords