Chemical Interrogation of Nuclear Size Identifies Compounds with Cancer Cell Line-Specific Effects on Migration and Invasion
Sign Up to like & getrecommendations! Published in 2022 at "ACS Chemical Biology"
DOI: 10.1021/acschembio.2c00004
Abstract: Background: Lower survival rates for many cancer types correlate with changes in nuclear size/scaling in a tumor-type/tissue-specific manner. Hypothesizing that such changes might confer an advantage to tumor cells, we aimed at the identification of… read more here.
Keywords: cell line; migration invasion; nuclear size; size ... See more keywords
PKC-mediated phosphorylation of nuclear lamins at a single serine residue regulates interphase nuclear size in Xenopus and mammalian cells
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e16-11-0786
Abstract: A novel PKC phosphorylation site in lamin B3 influences both nuclear lamina dynamics and nuclear size in Xenopus laevis embryos and extracts. PKC activity also modulates nuclear size in mammalian cell culture, and a conserved… read more here.
Keywords: nuclear size; size xenopus; size; pkc mediated ... See more keywords
Skyrme-type nuclear interaction as a tool for calculating the finite-nuclear-size correction to atomic energy levels and the bound-electron g factor
Sign Up to like & getrecommendations! Published in 2020 at "Physical Review A"
DOI: 10.1103/physreva.101.062502
Abstract: A state-of-the-art approach for calculating the finite nuclear size correction to atomic energy levels and the bound-electron $g$ factor is introduced and demonstrated for a series of highly charged hydrogen-like ions. Firstly, self-consistent mean-field calculations… read more here.
Keywords: finite nuclear; calculating finite; skyrme; nuclear size ... See more keywords
Ploidy and Size at Multiple Scales in the Arabidopsis Sepal[OPEN]
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DOI: 10.1105/tpc.18.00344
Abstract: Ploidy and size correlate at multiple biological scales (subcellular, cellular, and organismal), but compensation effects dampen the effect of ploidy change on organ size. Ploidy and size phenomena are observed to be correlated across several… read more here.
Keywords: nuclear size; ploidy size; ploidy; size ... See more keywords
Abstract 4331: Nuclear size of circulating tumor cells is associated with prognosis in metastatic, castration-resistant prostate cancer
Sign Up to like & getrecommendations! Published in 2020 at "Endocrinology"
DOI: 10.1158/1538-7445.am2020-4331
Abstract: Background: Current risk stratification models in prostate cancer (PC) have been based on clinical and pathological variables. Beyond serum prostate-specific antigen (PSA) concentration measurements, there remain few new biomarkers to help identify patients at risk… read more here.
Keywords: nuclear size; prostate cancer; size; circulating tumor ... See more keywords
Nuclear size rectification: A potential new therapeutic approach to reduce metastasis in cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.1022723
Abstract: Research on metastasis has recently regained considerable interest with the hope that single cell technologies might reveal the most critical changes that support tumor spread. However, it is possible that part of the answer has… read more here.
Keywords: metastasis; size rectification; nuclear size; rectification potential ... See more keywords