Identification and Characterization of the Nuclease Activity of the Extracellular Proteins from Salmonella enterica Serovar Typhimurium.
Sign Up to like & getrecommendations! Published in 2020 at "Current microbiology"
DOI: 10.1007/s00284-020-02201-1
Abstract: Pathogens have evolved an array of strategies to establish a productive infection. The extracellular proteins secreted by pathogens are one of unique mechanisms to evade the host innate immune response. Many secretory proteins transported by… read more here.
Keywords: nuclease activity; typhimurium; activity extracellular; activity ... See more keywords
Inhibition of nuclease activity by a splice-switching oligonucleotide targeting deoxyribonuclease 1 mRNA prevents apoptosis progression and prolong viability of normal human CD4+ T-lymphocytes.
Sign Up to like & getrecommendations! Published in 2020 at "Biochimie"
DOI: 10.1016/j.biochi.2020.04.009
Abstract: The nuclease activity of deoxyribonuclease 1 (DNase I) is regulated by alternative splicing (AS) of its mRNA. The aim of this study was to define the ability of a splice-switching oligonucleotide (SSO) that base-paired with… read more here.
Keywords: splice switching; nuclease activity; activity; mrna ... See more keywords
Corrigendum: MUS81 nuclease activity is essential for replication stress tolerance and chromosome segregation in BRCA2-deficient cells
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms16171
Abstract: This corrects the article DOI: 10.1038/ncomms15983. read more here.
Keywords: essential replication; mus81 nuclease; nuclease activity; replication stress ... See more keywords
Nuclease activity: an exploitable biomarker in bacterial infections
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Molecular Diagnostics"
DOI: 10.1080/14737159.2022.2049249
Abstract: ABSTRACT Introduction In the increasingly challenging field of clinical microbiology, diagnosis is a cornerstone whose accuracy and timing are crucial for the successful management, therapy, and outcome of infectious diseases. Currently employed biomarkers of infectious… read more here.
Keywords: biomarker bacterial; nuclease activity; exploitable biomarker; activity ... See more keywords
FAN1's protection against CGG repeat expansion requires its nuclease activity and is FANCD2-independent.
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic acids research"
DOI: 10.1093/nar/gkab899
Abstract: The Repeat Expansion Diseases, a large group of human diseases that includes the fragile X-related disorders (FXDs) and Huntington's disease (HD), all result from expansion of a disease-specific microsatellite via a mechanism that is not… read more here.
Keywords: protection; expansion; nuclease activity; fancd2 ... See more keywords