Articles with "nuclease wild" as a keyword



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WT-PE: Prime editing with nuclease wild-type Cas9 enables versatile large-scale genome editing

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Published in 2022 at "Signal Transduction and Targeted Therapy"

DOI: 10.1038/s41392-022-00936-w

Abstract: Large scale genomic aberrations including duplication, deletion, translocation, and other structural changes are the cause of a subtype of hereditary genetic disorders and contribute to onset or progress of cancer. The current prime editor, PE2,… read more here.

Keywords: large scale; prime editing; type cas9; nuclease wild ... See more keywords