Fusobacterium nucleatum impairs DNA mismatch repair and stability in patients with squamous cell carcinoma of the head and neck
Sign Up to like & getrecommendations! Published in 2022 at "Cancer"
DOI: 10.1002/cncr.34338
Abstract: Dysbiosis of the laryngeal microbiota has been demonstrated to the development of head and neck squamous cell carcinoma (HNSCC), but the association of Fusobacterium and Fusobacterium nucleatum (F. nucleatum) with DNA mismatch repair (MMR) and… read more here.
Keywords: fusobacterium nucleatum; cell carcinoma; head neck; squamous cell ... See more keywords
Fusobacterium nucleatum mediates endothelial damage and increased permeability following single species and polymicrobial infection
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Periodontology"
DOI: 10.1002/jper.21-0671
Abstract: Abstract Background Numerous lines of evidence link periodontal pathobionts and their virulence factors with endothelial damage. Most research has been conducted using single species infections at the exclusion of other periodontal microorganisms that have been… read more here.
Keywords: infection; polymicrobial infection; endothelial damage; permeability ... See more keywords
Expression, Purification, and Characterization of the Recombinant, Two-Component, Response Regulator ArlR from Fusobacterium nucleatum
Sign Up to like & getrecommendations! Published in 2022 at "Applied Biochemistry and Biotechnology"
DOI: 10.1007/s12010-021-03785-5
Abstract: Fusobacterium nucleatum is associated with the incidence and development of multiple diseases, such as periodontitis and colorectal cancer (CRC). Until now, studies have proved only a few proteins to be associated with such pathogenic diseases.… read more here.
Keywords: response regulator; expression; nucleatum; expression purification ... See more keywords
Modulation of Intratumoral Fusobacterium nucleatum to Enhance Sonodynamic Therapy for Colorectal Cancer with Reduced Phototoxic Skin Injury.
Sign Up to like & getrecommendations! Published in 2023 at "ACS nano"
DOI: 10.1021/acsnano.3c01308
Abstract: Intratumoral pathogens can contribute to cancer progression and affect therapeutic response. Fusobacterium nucleatum, a core pathogen of colorectal cancer (CRC), is an important cause of low therapeutic efficacy and metastasis. Thus, the modulation of intratumoral… read more here.
Keywords: nucleatum; therapy; colorectal cancer; enhance ... See more keywords
Effect of a bacteriocin-producing Streptococcus salivarius on the pathogen Fusobacterium nucleatum in a model of the human distal colon
Sign Up to like & getrecommendations! Published in 2022 at "Gut Microbes"
DOI: 10.1080/19490976.2022.2100203
Abstract: ABSTRACT The gut microbiome is a vast reservoir of microbes, some of which produce antimicrobial peptides called bacteriocins that may inhibit specific bacteria associated with disease. Fusobacterium nucleatum is an emerging human bacterial pathogen associated… read more here.
Keywords: crc; salivarius dpc6993; fusobacterium; nucleatum ... See more keywords
Fusobacterium nucleatum and its associated systemic diseases: epidemiologic studies and possible mechanisms
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oral Microbiology"
DOI: 10.1080/20002297.2022.2145729
Abstract: ABSTRACT Background Fusobacterium nucleatum (F. nucleatum) is an anaerobic oral commensal and the major coaggregation bridge organism linking early and late colonisers. In recent years, a large number of studies suggest that F. nucleatum is… read more here.
Keywords: systemic diseases; nucleatum associated; nucleatum; associated systemic ... See more keywords
Antagonistic interaction between two key endodontic pathogens Enterococcus faecalis and Fusobacterium nucleatum
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oral Microbiology"
DOI: 10.1080/20002297.2022.2149448
Abstract: ABSTRACT Background Endodontic infections are known to be caused by pathogenic bacteria. Numerous previous studies found that both Fusobacterium nucleatum and Enterococcus faecalis are associated with endodontic infections, with Fusobacterium nucleatum more abundant in primary… read more here.
Keywords: interaction; antagonistic interaction; nucleatum; enterococcus faecalis ... See more keywords
Periodontitis exacerbates atherosclerosis through Fusobacterium nucleatum-promoted hepatic glycolysis and lipogenesis.
Sign Up to like & getrecommendations! Published in 2023 at "Cardiovascular research"
DOI: 10.1093/cvr/cvad045
Abstract: AIMS Positive associations between periodontitis (PD) and atherosclerosis have been established, but the causality and mechanisms are not clear. We aimed to explore the causal roles of PD in atherosclerosis and dissect the underlying mechanisms.… read more here.
Keywords: glycolysis lipogenesis; glycolysis; exacerbates atherosclerosis; nucleatum ... See more keywords
Prognostic impact of the Fusobacterium nucleatum status in colorectal cancers
Sign Up to like & getrecommendations! Published in 2019 at "Medicine"
DOI: 10.1097/md.0000000000017221
Abstract: Abstract To investigate the clinicopathological features and prognostic impact of Fusobacterium nucleatum (F nucleatum) status in patients with colorectal cancer (CRC) and its relationships with microsatellite instability (MSI) status. Retrospective analysis of consecutive 91 CRC… read more here.
Keywords: status; nucleatum status; prognostic impact; crc ... See more keywords
Fecal Fusobacterium nucleatum as a predictor for metachronous colorectal adenoma after endoscopic polypectomy
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Gastroenterology and Hepatology"
DOI: 10.1111/jgh.15559
Abstract: Fusobacterium nucleatum is increasingly being recognized as an important risk factor in colorectal cancer and colorectal adenoma. Endoscopic polypectomy is associated with a decreased incidence of colorectal cancer; however, patients still suffer from a risk… read more here.
Keywords: fusobacterium nucleatum; endoscopic polypectomy; nucleatum; colorectal adenoma ... See more keywords
Fusobacterium nucleatum and cancer
Sign Up to like & getrecommendations! Published in 2022 at "Periodontology 2000"
DOI: 10.1111/prd.12426
Abstract: Abstract Accumulating evidence demonstrates that the oral pathobiont Fusobacterium nucleatum is involved in the progression of an increasing number of tumors types. Thus far, the mechanisms underlying tumor exacerbation by F. nucleatum include the enhancement… read more here.
Keywords: fusobacterium nucleatum; nucleatum; tumor; nucleatum cancer ... See more keywords