Evaluation of the correlation between KRAS mutated allele frequency and pathologist tumorous nuclei percentage assessment in colorectal cancer suggests a role for zygosity status
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DOI: 10.1136/jclinpath-2018-205085
Abstract: Evaluation of molecular tumour heterogeneity relies on the tumorous nuclei percentage (TNP) assessment by a pathologist, which has been criticised for being inaccurate and suffering from interobserver variability. Based on the ‘Big Bang theory’ which… read more here.
Keywords: status; nuclei percentage; tumorous nuclei; colorectal cancer ... See more keywords