Preparation of Thermo- and pH-Responsive Microgels Based on Complementary Nucleobase Molecular Recognition.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular rapid communications"
DOI: 10.1002/marc.202200239
Abstract: Complementary interactions between the natural nucleobases is one of the important ways of biomolecular recognition. Although scientists have introduced such supramolecular non-covalent interactions into biomimetic materials through different approaches in recent years, further research is… read more here.
Keywords: recognition; thermo responsive; microgels based; responsive microgels ... See more keywords
Direct Readout of Single Nucleobase Variations in an Oligonucleotide.
Sign Up to like & getrecommendations! Published in 2017 at "Small"
DOI: 10.1002/smll.201702011
Abstract: Direct, low-cost, label-free, and enzyme-free identification of single nucleobase is a great challenge for genomic studies. Here, this study reports that wild-type aerolysin can directly identify the difference of four types of single nucleobase (adenine,… read more here.
Keywords: dna; single nucleobase; nucleobase; direct readout ... See more keywords
Facile, cost-effective, nucleobase-mediated chemical deposition of solar absorber Cu2ZnSnS4 films
Sign Up to like & getrecommendations! Published in 2019 at "Applied Surface Science"
DOI: 10.1016/j.apsusc.2019.07.212
Abstract: Abstract Solar absorber Cu2ZnSnS4 (CZTS) films were uniformly deposited on Si/Mo substrates via a facile, cost-effective chemical bath deposition (CBD) by using ribonucleic acid (RNA) nucleobase uracil as the functional building block. The functional sites… read more here.
Keywords: nucleobase; cost; cost effective; facile cost ... See more keywords
Functional Analysis of the Role of Equilibrative Nucleobase Transporter 1 (ENBT1/SLC43A3) in Adenine Transport in HepG2 Cells.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2020.04.013
Abstract: Equilibrative nucleobase transporter 1 (ENBT1/SLC43A3) has recently been identified as a purine-selective nucleobase transporter. Although it is highly expressed in the liver, its role in nucleobase transport has not been confirmed yet in hepatocytes or… read more here.
Keywords: transport; nucleobase; hepg2 cells; enbt1 ... See more keywords
Nucleobase-Interaction-Directed Biomimetic Supramolecular Self-Assembly
Sign Up to like & getrecommendations! Published in 2022 at "Accounts of Chemical Research"
DOI: 10.1021/acs.accounts.2c00135
Abstract: Conspectus The design and fabrication of synthetic self-assembled systems that can mimic some biological features require exquisitely sophisticated components that make use of supramolecular interactions to attain enhanced structural and functional complexity. In nature, nucleobase… read more here.
Keywords: nucleobase interaction; complementary nucleobase; nucleobase interactions; nucleobase ... See more keywords
Quantifying Interactions of Nucleobase Atoms with Model Compounds for the Peptide Backbone and Glutamine and Asparagine Side Chains in Water.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemistry"
DOI: 10.1021/acs.biochem.8b00087
Abstract: Alkylureas display hydrocarbon and amide groups, the primary functional groups of proteins. To obtain the thermodynamic information that is needed to analyze interactions of amides and proteins with nucleobases and nucleic acids, we quantify preferential… read more here.
Keywords: water; nucleobase; interactions nucleobase; favorable amide ... See more keywords
3-Fluoro-2-mercuri-6-methylaniline nucleotide as a high-affinity nucleobase-specific hybridization probe.
Sign Up to like & getrecommendations! Published in 2019 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.9b00405
Abstract: A 3-fluoro-6-methylaniline nucleoside was synthesized, incorporated into an oligonucleotide and its ability to form mercury-mediated base pairs was studied. UV melting experiments revealed markedly increased duplex stability with thymine, gua-nine and cytosine opposite to the… read more here.
Keywords: nucleobase specific; probe; mercuri methylaniline; nucleobase ... See more keywords
Enzymatic Synthesis of Nucleobase-Modified Single-Stranded DNA Offers Tunable Resistance to Nuclease Degradation.
Sign Up to like & getrecommendations! Published in 2018 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.8b00816
Abstract: We synthesized long, nucleobase-modified, single-stranded DNA (ssDNA) using terminal deoxynucleotidyl transferase (TdT) enzymatic polymerization. Specifically, we investigated the effect of unnatural nucleobase size and incorporation density on ssDNA resistance to exo- and endonuclease degradation. We… read more here.
Keywords: degradation; dna; nucleobase modified; modified single ... See more keywords
Expanded Genetic Alphabets: Managing Nucleotides That Lack Tautomeric, Protonated, or Deprotonated Versions Complementary to Natural Nucleotides.
Sign Up to like & getrecommendations! Published in 2017 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.6b00193
Abstract: 2,4-Diaminopyrimidine (trivially K) and imidazo[1,2-a]-1,3,5-triazine-2(8H)-4(3H)-dione (trivially X) form a nucleobase pair with Watson-Crick geometry as part of an artificially expanded genetic information system (AEGIS). Neither K nor X can form a Watson-Crick pair with any… read more here.
Keywords: watson crick; pair; expanded genetic; nucleobase ... See more keywords
Spontaneous Emergence of Self-Replicating Molecules Containing Nucleobases and Amino Acids
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.9b10796
Abstract: The conditions that led to the formation of the first organisms and the ways that life originates from a lifeless chemical soup are poorly understood. The recent hypothesis of “RNA-peptide coevolution” suggests that the current… read more here.
Keywords: amino acids; nucleobase; replicating molecules; self ... See more keywords
Radical Cascade Dissociation Pathways to Unusual Nucleobase Cation Radicals.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Society for Mass Spectrometry"
DOI: 10.1021/jasms.2c00098
Abstract: We report unusual dissociations of protonated RNA nucleosides tagged with radical initiator groups at ribose 5'-O and furnished with a 2',3'-O-isopropylidene protecting group. The ions undergo collision-induced radical cascade dissociations starting at the radical initiator… read more here.
Keywords: cation radicals; cascade; cascade dissociations; radical cascade ... See more keywords