3-Fluoro-2-mercuri-6-methylaniline nucleotide as a high-affinity nucleobase-specific hybridization probe.
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DOI: 10.1021/acs.bioconjchem.9b00405
Abstract: A 3-fluoro-6-methylaniline nucleoside was synthesized, incorporated into an oligonucleotide and its ability to form mercury-mediated base pairs was studied. UV melting experiments revealed markedly increased duplex stability with thymine, gua-nine and cytosine opposite to the… read more here.
Keywords: nucleobase specific; probe; mercuri methylaniline; nucleobase ... See more keywords