Severe Acute Respiratory Syndrome Coronavirus 2 Nucleocapsid Protein in the Ocular Tissues of a Patient Previously Infected With Coronavirus Disease 2019.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2020.3962
Abstract: Importance Coronavirus disease 2019 (COVID-19) has been recognized as a pandemic by the World Health Organization. Whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can also infect tissues besides the respiratory system, such as the… read more here.
Keywords: ocular tissues; previously infected; nucleocapsid protein; patient previously ... See more keywords
Probing Mercaptobenzamides as HIV Inactivators via Nucleocapsid Protein 7
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DOI: 10.1002/cmdc.201700141
Abstract: Human immunodeficiency virus type 1 (HIV‐1) nucleocapsid protein 7 (NCp7), a zinc finger protein, plays critical roles in viral replication and maturation and is an attractive target for drug development. However, the development of drug‐like molecules that… read more here.
Keywords: anti hiv; nucleocapsid protein; hiv activity; activity ... See more keywords
Nucleocapsid protein of SARS‐CoV‐2 is a potential target for developing new generation of vaccine
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24479
Abstract: SARS‐CoV‐2 has spread worldwide causing more than 400 million people with virus infections since early 2020. Currently, the existing vaccines targeting the spike glycoprotein (S protein) of SARS‐CoV‐2 are facing great challenge from the infection… read more here.
Keywords: nucleocapsid protein; developing new; new generation; protein sars ... See more keywords
The utility of SARS‐CoV‐2 nucleocapsid protein in laboratory diagnosis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24534
Abstract: The Coronavirus Disease 2019 (COVID‐19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), which has now become a global pandemic owing to its high transmissibility. The SARS‐CoV‐2 nucleocapsid protein tests are playing… read more here.
Keywords: nucleocapsid protein; cov nucleocapsid; sars cov; utility sars ... See more keywords
N‐terminally truncated nucleocapsid protein of SARS‐CoV‐2 as a better serological marker than whole nucleocapsid protein in evaluating the immunogenicity of inactive SARS‐CoV‐2
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Medical Virology"
DOI: 10.1002/jmv.26541
Abstract: The coronavirus disease 2019 pandemic caused by severe acute respiratory syndrome‐coronavirus 2 (SARS‐CoV‐2) had led to a serious public health crisis, and no specific treatments or vaccines are available yet. A nucleocapsid protein (NP)‐based enzyme‐linked… read more here.
Keywords: inactive sars; terminally truncated; better serological; sars cov ... See more keywords
TRIM21 promotes ubiquitination of SARS‐CoV‐2 nucleocapsid protein to regulate innate immunity
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28719
Abstract: The innate immune response is the first line of host defense against viral infections, but its role in immunity against SARS‐CoV‐2 remains unclear. By using immunoprecipitation coupled with mass spectroscopy, we observed that the E3… read more here.
Keywords: nucleocapsid protein; trim21; cov nucleocapsid; innate ... See more keywords
Mutations in the phosphorylation sites of SARS-CoV-2 encoded nucleocapsid protein and structure model of sequestration by protein 14-3-3
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and Biophysical Research Communications"
DOI: 10.1016/j.bbrc.2020.08.024
Abstract: Abstract SARS-CoV-2 is the etiologic agent of COVID-19. There is currently no effective means of preventing infections by SARS-CoV-2, except through restriction of population movement and contact. An understanding of the origin, evolution and biochemistry… read more here.
Keywords: protein; sequestration; nucleocapsid protein; phosphorylation sites ... See more keywords
Genus-specific pattern of intrinsically disordered central regions in the nucleocapsid protein of coronaviruses
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DOI: 10.1016/j.csbj.2020.07.005
Abstract: Abstract The nucleocapsid (N) protein is conserved in all four genera of the coronaviruses, namely alpha, beta, gamma, and delta, and is essential for genome functionality. Bioinformatic analysis of coronaviral N sequences revealed two intrinsically… read more here.
Keywords: pattern intrinsically; disordered central; specific pattern; genus specific ... See more keywords
The integrity of PRRSV nucleocapsid protein is necessary for up-regulation of optimal interleukin-10 through NF-κB and p38 MAPK pathways in porcine alveolar macrophages.
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DOI: 10.1016/j.micpath.2017.04.036
Abstract: Porcine reproductive and respiratory syndrome (PRRS), a highly contagious disease, has been constantly causing huge economic losses all over the world. PRRS virus (PRRSV) infection results in immunosuppression and IL-10 up-regulation. The relationship between them… read more here.
Keywords: protein; alveolar macrophages; prrsv nucleocapsid; porcine alveolar ... See more keywords
Identification and characterization of linear B cell epitopes on the nucleocapsid protein of porcine epidemic diarrhea virus using monoclonal antibodies
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DOI: 10.1016/j.virusres.2020.197912
Abstract: Abstract The nucleocapsid (N) protein of porcine epidemic diarrhea virus (PEDV), the most important pathogen causing severe diarrhea in piglets, is a highly conserved structural protein. In this study, 5 monoclonal antibodies (McAbs) against the… read more here.
Keywords: protein; porcine epidemic; pedv; protein porcine ... See more keywords
Capacitive Aptasensor Coupled with Microfluidic Enrichment for Real-Time Detection of Trace SARS-CoV-2 Nucleocapsid Protein
Sign Up to like & getrecommendations! Published in 2022 at "Analytical Chemistry"
DOI: 10.1021/acs.analchem.1c04296
Abstract: The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has lasted for almost 2 years. Stemming its spread has posed severe challenges for clinical virus detection. A long turnaround time, complicated operation, and… read more here.
Keywords: nucleocapsid protein; time; detection; real time ... See more keywords