Extracellular Adhesive Cues Physically Define Nucleolar Structure and Function
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202105545
Abstract: Adhesive cues from the extracellular matrix (ECM) specify the size and shape of the nucleus via mechanical forces transmitted through the cytoskeleton. However, the effects of these biophysical stimuli on internal nuclear architecture and cellular… read more here.
Keywords: structure function; extracellular adhesive; nucleolar structure; adhesive cues ... See more keywords
Use of the iNo score to discriminate normal from altered nucleolar morphology, with applications in basic cell biology and potential in human disease diagnostics
Sign Up to like & getrecommendations! Published in 2018 at "Nature Protocols"
DOI: 10.1038/s41596-018-0044-3
Abstract: Ribosome biogenesis is initiated in the nucleolus, a cell condensate essential to gene expression, whose morphology informs cancer pathologists on the health status of a cell. Here, we describe a protocol for assessing, both qualitatively… read more here.
Keywords: ino score; nucleolar structure; cell; biology ... See more keywords