Nucleoli in epithelial cell collectives respond to tumorigenic, spatial, and mechanical cues
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DOI: 10.1091/mbc.e22-02-0070
Abstract: Cancer cells are known to have larger nucleoli, consistent with their higher transcriptional and translational demands. Meanwhile, on stiff extracellular matrix, normal epithelial cells can exhibit genomic and proteomic mechanoactivation toward tumorigenic transformations, such as… read more here.
Keywords: cell; epithelial cell; mechanical cues; cell collectives ... See more keywords