LncRNA H19 is involved in myocardial ischemic preconditioning via increasing the stability of nucleolin protein
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29524
Abstract: Myocardial ischemic preconditioning (IP) is defined as a brief period of myocardial ischemia/reperfusion (I/R) that significantly reduces injury during the subsequent exposure to long‐term I/R. However, the underlying mechanisms of myocardial IP are yet to… read more here.
Keywords: protein; myocardial ischemic; lncrna h19; nucleolin ... See more keywords
Nucleolin is expressed in patient‐derived samples and glioblastoma cells, enabling improved intracellular drug delivery and cytotoxicity
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Cell Research"
DOI: 10.1016/j.yexcr.2018.06.005
Abstract: ABSTRACT One of the major challenges in Glioblastoma (GBM) therapy relates with the existence of glioma stem‐like cells (GSCs), known to be chemo‐ and radio‐resistant. GSCs and non‐stem GBM cells have the ability to interchange,… read more here.
Keywords: drug delivery; derived samples; nucleolin; glioblastoma cells ... See more keywords
Biophysical Characterization of Nucleolin Domains Crucial for Interaction with Telomeric and TERRA G-Quadruplexes.
Sign Up to like & getrecommendations! Published in 2023 at "Biochemistry"
DOI: 10.1021/acs.biochem.2c00641
Abstract: Nucleolin (NCL) is a well-characterized nucleic acid-binding protein; it binds to various canonical and noncanonical structures including single- and double-stranded DNA and RNA, hairpin, loops, and G-quadruplex structures. G-quadruplex structures are majorly formed in promoter,… read more here.
Keywords: characterization nucleolin; biophysical characterization; rna; nucleolin ... See more keywords
Seneca Valley Virus 3Cpro Mediates Cleavage and Redistribution of Nucleolin To Facilitate Viral Replication
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.00304-22
Abstract: The nucleolus is a subnuclear cellular compartment, and nucleolin (NCL) resides predominantly in the nucleolus. NCL participates in viral replication, translation, internalization, and also serves as a receptor for virus entry. ABSTRACT Seneca Valley virus… read more here.
Keywords: cleavage; viral replication; seneca valley; replication ... See more keywords
Nucleolin Overexpression Predicts Patient Prognosis While Providing a Framework for Targeted Therapeutic Intervention in Lung Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14092217
Abstract: Simple Summary Despite the clinical benefit of new anticancer therapies, such as immune checkpoint inhibitors, lung cancer remains the most frequent cause of cancer-related death worldwide, thus supporting the need to develop novel anticancer treatments.… read more here.
Keywords: lung cancer; pulmonary carcinomas; overexpression; nucleolin ... See more keywords